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Adhesives for Molecular Diagnostic Instruments | MasterBond.com

Medical Grade Compounds for Molecular Diagnostic Instruments

With the proliferation of infectious diseases such as the latest strain of the coronavirus i.e Covid-19 worldwide, there is a critical need to develop tests, which can detect patients who have contracted the disease. Master Bond has been developing specialty medical grade adhesives, sealants, coatings, impregnation materials, and encapsulation compounds for medical device companies, which are the forefront of designing and manufacturing instruments that can detect such diseases. Molecular diagnostic technology and instruments are widely employed and recognized as not only an efficient and fast method of detecting diseases, but also as an accurate and reliable tool.

Master Bond has been helping medical device customers over the years, and our products have been widely employed in biosensors, microfluidic applications, and in the assembly of diagnostic instruments. One example is our structural adhesive EP31, which was successfully used for bonding acrylic and aluminum components, in a molecular diagnostic instrument, for a non-instrumented nucleic acid amplification system.1

Many Master Bond products meet the USP Class VI and/or ISO10993-5 test requirements. Some examples of systems which meet both USP Class VI for biocompatibility and ISO10993-5 for cytotoxicity are:



Product Key Features Typical Use
EP30Med Two component room temperature curable, epoxy
Low viscosity, and optically clear
Biosensors2
Diagnostic tools
EP62-1Med Two component, moderate heat curable, epoxy
Highly sterilization resistant
Electrosurgical equipment3
RFID equipment4
EP42HT-2Med Two component, room temperature curable, epoxy
Repeated autoclave resistant
Implantable sensors5
Drug delivery MEMS device6
MasterSil 151Med Two component room temperature curable, silicone
Highly flexible
Implantable electrical nerve stimulation equipment7

Sources

1Kubota, Ryo. Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, Honolulu, HI. Diagenetics, Inc, Honolulu, HI; Labarre Paul. Program for Appropriate Technologies in Health (PATH), Seattle, WA. Weigl, Bernhard H. (PATH), Seattle, WA. Li, Yong. Nutrition, Food, and Animal Science, University of Hawaii at Manoa, Honolulu, HI. Haydock. Paul, Blood Cell Storage Inc (BCSI), Seattle, WA. Jenkins, Daniel M. Molecular Biosciences and Bioengineering, University of Hawaii at Manoa, Honolulu, HI. “Molecular diagnostics in a teacup: Non-Instrumented Nucleic Acid Amplification (NINA) for rapid, low cost detection of Salmonella enteric.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251779/

2To, Gary; Mahfouz, Mohamed. Center for Musculoskeletal Research The University of Tennessee. Qu, Wenchao; Islama, Syed K., Department of Electrical Engineering The University of Tennessee, Knoxville, TN. “Multi-channels wireless strain mapping instrument for total knee arthoplasty with 30 microcantilevers and ASIC Technology.” https://warwick.ac.uk/fac/sci/eng/research/grouplist/sensorsanddevices/mbl/database/ieeesensors08/PDFs/Papers/280_6396.pdf

3United States Patent Application Publication, Pub. No.: US 2013/0057390 A1. Pub. Date: Mar. 7, 2013. Radio Frequency Identification Tags For Use In Extreme Environments. Inventors: David Watt, Newark, CA. Fay, Stanford, CA. Jose Joseph, Palo Alto, CA.Karen Marie Nashold, San Francisco, CA. David Watters, Sunnyvale, CA. http://www.freepatentsonline.com/y2013/0057390.html

4United States Patent Van Wyk et al. Patent No.: US 8,486,064 B2. Date of Patent: Jul. 16, 2013. Electrosurgical Device Having Floating-Potential Electrode and Curvilinear Profile. Inventors: Robert A. Van Wyk, St. Pete Beach, FL. Yuval Carmel, Rockville, MD. Anatoly Shkvarunets, Rockville, MD.

5Baj-Rossi, C., et al. “Biocompatible Packagings for Fully Implantable Multi-Panel Devices for Remote Monitoring of Metabolism,” 2015 IEEE Biomedical Circuits and Systems Conference (BioCAS), Atlanta, GA, 2015, pp. 1-4. doi: 10.1109/BioCAS.2015.7348398. Accessed 17 Jan. 2018. https://icwww.epfl.ch/~demichel/publications/archive/2015/BioCAS-2015_Biocampatible-Packagings-(Camilla).pdf

6Yawen Lia, Rebecca S. Shawgo, Betty Tyler, Paul T. Hendersonc, John S. Vogel, Aron Rosenberg, Phillip B. Storm, Robert Langer, Henry Brem, Michael J. Cima. Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, Department of Neurological Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, Biology and Biotechnology Research Program and Center for Accelerator Mass Spectrometry, Lawrence Livermore National Laboratory, Livermore, CA, Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA. "In vivo release from a drug delivery MEMS device." September 2004. https://www.sciencedirect.com/science/article/abs/pii/S0168365904003827

7Moen, Lars Lyse. Norwegian University of Science and Technology, Department of Engineering Cybernetics. "An Implantable Device for Electrical Nerve Stimulation." July 2014.

Medical Grade Adhesives for Molecular Diagnostic Instruments

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